![]() ![]() Women who survived to age 90 years with intact mobility and cognitive function were healthier at baseline compared with women who survived without those outcomes or who did not survive to age 90 years (eg, 143 women vs 101 women and 202 women with 0 chronic conditions). Results Among 1813 women, there were 464 women (mean age at baseline, 71.6 years) who survived to age 90 years with intact mobility and cognitive functioning, 420 women (mean age at baseline, 71.3 years) who survived to age 90 years without intact mobility and cognitive functioning, and 929 women (mean age at baseline, 70.2 years) who did not survive to age 90 years. Main Outcomes and Measures Using multinomial logistic regression, odds ratios (ORs) and 95% CIs were estimated for 3 healthy longevity outcomes for each clock: survival to age 90 years with intact mobility, survival to age 90 years without intact mobility, and no survival to age 90 years. Data were analyzed from December 2020 to July 2021.Įxposures EAA was estimated using 4 established “clocks”: Horvath pantissue, Hannum, Pheno, and Grim. ![]() Median (IQR) follow-up times from baseline were 21.6 (19.6-22.9) years and 21.4 (19.8-22.7) years for women who survived to age 90 years with and without intact mobility, respectively, and 13.2 (8.8-16.7) for women who did not survive to age 90 years. ![]() This study was restricted to women with genome-wide DNA methylation data, generated from baseline blood samples within 3 WHI ancillary studies. Participants were located in multiple centers. Objective We investigated associations between epigenetic age acceleration (EAA), a biomarker associated with aging, and healthy longevity among older women.ĭesign, Setting, and Participants This cohort study was a secondary analysis of participants in the Women’s Health Initiative (WHI) who were eligible to survive to age 90 years by September 30, 2020. ![]() Importance Accelerated biological aging is associated with decreased physical capability and cognitive functioning, which are associated with increased risk of morbidity and mortality. Shared Decision Making and Communication.Scientific Discovery and the Future of Medicine.Health Care Economics, Insurance, Payment.Clinical Implications of Basic Neuroscience.Challenges in Clinical Electrocardiography.meanings of chronological age will be translated. Input a term chronological age by either copy & post, drag & drop, or simply by typing in the search box. What is 'chronological age' meaning in English? This page is an online lexical resource, contains a list of the chronological age like words in a English language in the order of the alphabets, and that tells you what they mean, in the same or other languages including English. Indian Official Languages Dictionary is significantly better than Google translation offers multiple meanings, alternate words list of chronological age chronological age phrases with similar meanings in English, English dictionary English chronological age translation chronological age meaning chronological age definition chronological age antonym chronological age synonym English language reference work for finding synonyms, antonyms of chronological age. Thesaurus: Synonym & Antonym of chronological age Chronological age | English dictionary translates English to English and English to English chronological age words chronological age phrases with chronological age synonyms chronological age antonyms chronological age pronunciations.Ĭhronological age in English English of translation of chronological age English meaning of chronological age what is chronological age in English dictionary definition, antonym, and synonym of chronological age ![]()
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